Speakers: CSV2024: 5th Symposium of the Canadian Society for Virology

Kanta Subbarao
Professor
University of Melbourne

Professor Kanta Subbarao is a virologist and a physician with specialty training in paediatrics and paediatric infectious diseases. She has worked on molecular virology and vaccine development for emerging viruses that pose a potential pandemic threat, including influenza viruses, SARS and MERS and now SARS-CoV-2 coronaviruses in a career spanning 30 years. Previously, she was Chief of the Molecular Genetics Section of the Influenza Branch at the Centers for Disease Control and Prevention (CDC) in Atlanta (1997-2002) and Chief of the Emerging Respiratory Viruses Section of the Laboratory of Infectious Diseases, of the National Institute of Allergy and Infectious Diseases (NIAID), NIH in the USA (2002-2016). In November 2016, she moved to Melbourne and the Peter Doherty Institute for Infection and Immunity. She is a Fellow of the Australian Academy of Health and Medical Sciences, American Academy of Microbiology and the Infectious Diseases Society of America. She serves on the Editorial Board of PLoS Pathogens, Cell Host and Microbe, Journal of Virology, Med, and Cell.

Nevan Krogan

Nevan Krogan, PhD, is a molecular biologist, UC San Francisco professor, and director of the intensely interdisciplinary Quantitative Biosciences Institute (QBI) under the UCSF School of Pharmacy. He is also a senior investigator at the Gladstone Institutes.

He led the work to create the SARS-CoV-2 interactome and assembled the QBI Coronavirus Research Group (QCRG), which includes hundreds of scientists from around the world. His research focuses on developing and using unbiased, quantitative systems approaches to study a wide variety of diseases with the ultimate goal of developing new therapeutics.

Nevan serves as Director of The HARC Center, an NIH-funded collaborative group that focuses on the structural characterization of HIV-human protein complexes. Dr. Krogan is also the co-Director of three Cell Mapping initiatives, the Cancer Cell Mapping Initiative (CCMI), the Host Pathogen Map Initiative (HPMI) and the Psychiatric Cell Map Initiative (PCMI). These initiatives map the gene and protein networks in healthy and diseased cells with these maps being used to better understand disease and provide novel therapies to fight them.

He has authored over 250 papers in the fields of genetics and molecular biology and has given over 350 lectures and seminars around the world. He is a Searle Scholar, a Keck Distinguished Scholar, and was recently awarded the Roddenberry Prize for Biomedical Research.

Emerging Viruses

Speaker Type	First Name	Last Name	Company / Affiliation	Job Title	Abstract Title
Session Chair	Angela	Rasmussen	Vaccine and Infectious Disease Organization/University of Saskatchewan	Research Scientist/Adjunct Professor	(not set)
Session Chair	Mariana	Baz	Université Laval	Assistant Professor	(not set)
Speaker	Ryan	Noyce	University of Alberta	Assistant Professor	Exploring novel virus-host interactions to emerging poxviruses and the development of next-generation virus-vectored vaccines
Abstract Presenter	Kaushal	Baid	Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan	Postdoctoral researcher	SARS-CoV-2 induces a differential immune response in insectivorous bat cells relative to human cells.
Abstract Presenter	Natacha	Ogando	University of Alberta	Postdoctoral Fellow	Discovering the molecular mechanisms driving neuropsychiatric post-acute sequelae of COVID-19 (neuroPASC).
Abstract Presenter	Yannick	Galipeau	University of Ottawa	PhD student	Autoantibodies Targeting Angiotensin Converting Enzyme 2 Are Not Induced Following SARS-CoV-2 Infection
Abstract Presenter	Olus	Uyar	Institut national de la recherche scientifique	Postdoc	Spatio-temporal rewiring of the endolysosomal network by Zika virus and Dengue virus
Abstract Presenter	Calvin	Ezeanyaegbu	Memorial University	Graduate student	Elucidating SARS-CoV-2 Inflammatory Responses: ORF3a-Induced Inflammasome Activation and Bystander Mechanisms in Lung Epithelial and Macrophage Cell Lines

Fundamental Virology

Speaker Type	First Name	Last Name	Company / Affiliation	Job Title	Abstract Title
Session Chair	Laurent	Chatel-Chaix	Institut National de la Recherche Scientifique	Associate Professor	(not set)
Session Chair	Marceline	Côté	University of Ottawa	Associate Professor	(not set)
Speaker	Trushar	Patel	University of Lethbridge	Canada Research Chair and Associate Professor	(not set)
Abstract Presenter	Justine	Kniert	University of Alberta	Graduate Student	Reovirus core factories coalesce and obtain outercapsid proteins as infection progresses into perinuclear regions
Abstract Presenter	Juliette	Bougon	Dalhousie University	Postdoctoral Fellow	Functional interplay between PA-X and NS1 in mediating host shutoff and nuclear PABPC1 accumulation during influenza A virus infection
Abstract Presenter	Rory	Mulloy	University of Calgary	PhD student	SARS-CoV-2 produces a truncated nucleocapsid proteoform that enhances virus fitness and immune evasion
Abstract Presenter	Megha	Rohamare	University of Saskatchewan	Student	Development of SARS-Coronavirus-2 replication tools to study emerging variants
Abstract Presenter	Breanna	Landry	University of British Columbia	Graduate Student	Exploring NS2A?: Characterization and Roles in Flaviviral Replication and Virion Assembly
Abstract Presenter	Nazia Yasin	Thakur	The Pirbright Institute	PhD Student	Understanding the risk of bat sarbecovirus spillover into humans � correlating host range, affinity and antigenicity.
Abstract Presenter	Redaet	Daniel	University of Ottawa	PhD Candidate	Impacts of Arl8b-dependent lysosome positioning on Ebola virus entry
Abstract Presenter	Kathryn	Rozen-Gagnon	University of Toronto	Assistant Professor	Chikungunya virus relies on mosquito-specific miRNAs for efficient salivary gland secretion

Virus-Host Interactions - A

Speaker Type	First Name	Last Name	Company / Affiliation	Job Title	Abstract Title
Session Chair	Joyce	Wilson	University of Saskatchewan	Professor	(not set)
Session Chair	Kathryn	Rozen-Gagnon	University of Toronto	Principal Investigator	(not set)
Speaker	Selena	Sagan	University of British Columbia	Professor	(not set)
Abstract Presenter	Cassandra	Edgar	Western University	Graduate Student	The Regulation of the Checkpoint Receptor Tim-3 by the HIV-1 Accessory Protein Vpu
Abstract Presenter	Mariel	Kleer	University of Calgary	PhD Student	The kaposin RNA transcript is the architect of a successful KSHV infection
Abstract Presenter	Yuhang	Luo	MCGILL UNIVERSITY	PhD candidate	IFITM1 inhibits the entry of Nipah and Hendra viruses by sequestering the ephrinB2 receptor in rigid membrane nanodomains.
Abstract Presenter	Michael	Norris	University of Toronto	Assistant Professor	The Critical Role of Lipids in Measles and Nipah Virus Assembly: Insights for Antiviral Design

Virus-Host Interactions - B

Speaker Type	First Name	Last Name	Company / Affiliation	Job Title	Abstract Title
Session Chair	Joyce	Wilson	University of Saskatchewan	Professor	(not set)
Session Chair	Kathryn	Rozen-Gagnon	University of Toronto	Principal Investigator	(not set)
Abstract Presenter	Juveriya Qamar	Khan	University of Saskatchewan	Graduate Student	Genome-wide CRISPR screens reveals unique host-directed inhibitor drugs and a pro-viral signaling pathway for SARS-CoV-2
Abstract Presenter	Eric	Pringle	Dalhousie Universitiy	Postdoctoral Fellow	KSHV lytic replication requires eIF3D
Abstract Presenter	Roger	Lippé	University of Montreal	Principal Investigator	HSV-1 and Alzheimer's disease. A molecular link
Abstract Presenter	Jonathan	Owen	Emory University	PhD Student	Membrane tethering by the host GTPase Atlastin-2 is critical for flavivirus replication
Abstract Presenter	Nicholas	Denniston	Queens University	Graduate Student	The Role of HSV pUL16 in Altering Host Mitochondrial Physiology

Virus Evolution

Speaker Type	First Name	Last Name	Company / Affiliation	Job Title	Abstract Title
Session Chair	Finlay	Maguire	Dalhousie University	Assistant Professor	(not set)
Session Chair	Jeff	Joy	University of British Columbia/BC Centre for Excellence in HIV/AIDS	Professor/Senior Scientist	(not set)
Speaker	Francois	Cholette	Public Health Agency of Canada	Biologist	(not set)
Abstract Presenter	Stephen	Lee	University of Alberta	Graduate Student	Evolution by exclusion: wildtype poxviruses interfere with selection for cidofovir-resistant mutants in coinfected cells
Abstract Presenter	Candice	Lemaille	University of Manitoba	Master's Student	Monkeypox surveillance in GBMSM, sex workers and PLWH in Kenya
Abstract Presenter	Sophie	Gobeil	Université Laval	Assistant professor	Evolution of the S protein over the course of the COVID-19 pandemic

One Health

Speaker Type	First Name	Last Name	Company / Affiliation	Job Title	Abstract Title
Session Chair	Samira	Mubareka	Sunnybrook Health Sciences Centre	Microbiologist	(not set)
Session Chair	Katharine	Magor	University of Alberta	Professor	(not set)
Speaker	Arinjay	Banerjee	Vaccine and Infectious Disease Organization, University of Saskatchewan	Prinicpal Scientist	A field-to-lab approach to investigate the drivers of bat borne zoonotic viruses
Abstract Presenter	Victoria	Gonzalez	Vaccine Infectious Disease Organization, University of Saskatchewan	PhD Student	Canonical and non-canonical features of the bat interferon response against coronaviruses
Abstract Presenter	Jordan	Wight	Memorial University of Newfoundland	PhD Candidate	Avian influenza virus circulation and immunity in a wild urban duck population prior to and during a highly pathogenic H5N1 outbreak
Abstract Presenter	Giulia	Gallo	The Pirbright Institute	Postdoctoral Fellow	Insight into the scope of alphacoronavirus receptor usage

Vaccines & Antivirals

Speaker Type	First Name	Last Name	Company / Affiliation	Job Title	Abstract Title
Session Chair	Matthias	Gotte	University of Alberta	Professor	(not set)
Session Chair	Alyson	Kelvin	Vaccine and Infectious Disease Organization International Vaccine Centre	Scientist	(not set)
Speaker	Andrés	Finzi	Université de Montréal and researcher at the Centre de Recherche du CHUM (CRCHUM)	Professor	An asymmetric opening of HIV-1 Env sensitizes HIV-1-infected cells to ADCC
Abstract Presenter	Corby	Fink	Robarts Research Institute, Western University	Postdoctoral Fellow	Pheophorbide is a potent in vivo antiviral during SARS-CoV-2 infection
Abstract Presenter	Melanie	Goens	University of Guelph	Graduate Student	Development of Newcastle disease virus vectored vaccine against Nipah virus
Abstract Presenter	Josh	Wu	Defence Research and Development Canada	Defence Sceintist	A single administration of interferon alpha expressed from an adenovirus vector protects mice from the lethal challenge of eastern equine encephalitis virus
Abstract Presenter	Stephanie	DeWitte-Orr	Wilfrid Laurier University	Associate Professor	Using long, sequence specific dsRNA to knockdown viral and host proteins with antiviral effects via RNAi
Abstract Presenter	Wenguang	Cao	National Microbiology Laboratory, PHAC	Lab Biologist	Comparative Analysis of Atypical and Acute Ebola Virus Disease in Ferrets Treated with Monoclonal Antibody

Putting Viruses to Work

Speaker Type	First Name	Last Name	Company / Affiliation	Job Title	Abstract Title
Session Chair	Maya	Shmulevitz	University of Alberta	Prinicipal Investigator	(not set)
Session Chair	Sarah	Wootton	University of Guelph	Associate Professor	(not set)
Speaker	Sam	Workenhe	University of Guelph	Assistant Professor	(not set)
Abstract Presenter	Suzy (Jun Li)	Wang	University of Alberta	Graduate Student	Turning cold tumours hot: utilizing engineered vaccinia virus to increase tumour immunogenicity
Abstract Presenter	Tommy	Alain	CHEO RI, uOTTAWA	Senior Scientist, Associate Professor	Reovirus as a novel platform for orally available cancer vaccine
Abstract Presenter	Amy	Gillgrass	McMaster University	Assistant Professor	Combating the HIV/TB co-infection syndemic: Testing a novel mucosal adenoviral TB vaccine in na�ve and HIV-infected humanized mice
Abstract Presenter	Aida	Said	University of Ottawa	PhD student	Deciphering translation dynamics during oncolysis: translatome of glioblastoma cells undergoing Maraba virus MG1 infection

Veterinary Viruses

Speaker Type	First Name	Last Name	Company / Affiliation	Job Title	Abstract Title
HPAI Update	Matthew	Miller	McMaster University	Executive Director, M.G. DeGroote Institute for Infectious Disease Research	(not set)
HPAI Update	Yan	Zhou	VIDO	Principal Scientist	(not set)
HPAI Update	Jeff	Joy	University of British Columbia/BC Centre for Excellence in HIV/AIDS	Professor/Senior Scientist	(not set)
HPAI Update	Samira	Mubareka	Sunnybrook Health Sciences Centre	Microbiologist	(not set)
HPAI Update	Frank	van der Meer	University of Calgary Veterinary Medicine	Professor	(not set)
Session Chair	Qiang	Liu	University of Saskatchewan	Senior Scientist	(not set)
Session Chair	Suresh	Tikoo	School of Public Health/VIDO, University of Saskatchewan	Professor/Senior Scientist	(not set)
Session Chair	Frank	van der Meer	University of Calgary Veterinary Medicine	Professor	(not set)
Abstract Presenter	Mirzabek	Kazbekov	University of Alberta	Graduate Student	Influenza NS1 inhibits RIPLET activated RIG-I signaling in avian cells.
Abstract Presenter	Rita Maria	Quintela Tizon	Vaccine and Infectious Disease Organization (VIDO) / University of Saskatchewan	PhD student	Evolution of Interferon beta specificity in humans and bats may be responsible for differences in viral pathogenesis.
Abstract Presenter	Ulises	Barron-Castillo	University of Saskatchewan	PhD Student	Intranasal vaccination of an elastase-dependent replication defective influenza virus vaccine provides protection against drifted IAV H3N2 infection in swine
Abstract Presenter	Ayumi	Matsuyama	Western College of Veterinary Medicine, University of Saskatchewan	Post-Doctoral Fellowship	Characterization of immune cell subsets in broiler chickens following challenge with variant infectious bursal disease virus

SPEAKERS